Volume 7 - Issue 12, December 2025


Download the issue as single pdf with all articles: IJHSR 2025 Vol. 7 Issue 12

IJHSR ISSN (Online Version): 2642 1054
IJHSR ISSN (Print Version): 2642 1046


Clinical Insight into Gene Editing Using CRISPR-Cas9

Avnika R. Kandala

Meriden School, 3 Margaret St, Strathfield, Sydney, NSW, 2135, Australia; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 1-15
Download Article: https://doi.org/10.36838/v7i12.1

KEYWORDS: Translational Medical Sciences, Disease Treatment and Therapies, Gene Editing, In vivo, Ex vivo.


Identifying Biomarkers in Different Demographics of Alzheimer's Patients

Krishna Iyer

South Brunswick High School, 750 Ridge Rd, Monmouth Junction, New Jersey, 08852, USA; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 16-22
Download Article: https://doi.org/10.36838/v7i12.16

KEYWORDS: Computational Biology and Bioinformatics, Computational Neuroscience, Machine Learning, Disease Detection and Diagnosis, Alzheimer’s Disease.


Hydration as a Potential Modulator of Body Composition in Males and Females: A Literature Review

Niraj Shah

Gretchen Whitney High School, 16800 Shoemaker Ave, Cerritos, CA 90703, USA; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 23-27
Download Article: https://doi.org/10.36838/v7i12.23

KEYWORDS: Biomedical and Health Sciences, Nutrition and Natural Products, Hydration, Water Intake, Body Composition, Obesity and Overweight.


Histone Modifications in Alzheimer's Disease: Both a Sign and a Remedy

Amy Joseph

St Christopher’s School, Building 119, 841 Road No 4109, PO Box 32052, Isa Town, Bahrain; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 28-36
Download Article: https://doi.org/10.36838/v7i12.28

KEYWORDS: Biomedical and Health Sciences, Genetics and Molecular Biology of Disease, Alzheimer’s Disease, Epigenetics, Histone Modifications.


Saltwater to Stars: Exploring the Effects of Space Conditions on the Early Development of Artemia

Yanting (Kelly) Liu

Pinehurst School, 75 Bush Road, Albany, Auckland 0632, New Zealand; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 37-46
Download Article: https://doi.org/10.36838/v7i12.37

KEYWORDS: Animal Sciences, Development, Artemia, Cryptobiosis, Embryonic Resilience.


Mitigating QR Code Fraud: Algorithmic Vulnerabilities, Exploitation, and a Verification-Based Trust Framework

Navya Agarwal

Dhirubhai Ambani International School, G Block Bandra Kurla Complex, Bandra East, Mumbai, Maharashtra, 400098, India; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 47-55
Download Article: https://doi.org/10.36838/v7i12.47

KEYWORDS: Systems Software, Cybersecurity, QR Code Security, Phishing Detection, Verification Framework.


Quantifying and Visualizing Fluoride Induced Tooth Mineralization

Wenxuan Feng

Australian International School, 1 Lorong Chuan, Singapore 556818; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 56-63
Download Article: https://doi.org/10.36838/v7i12.56

KEYWORDS: Chemistry, Inorganic Chemistry, Tooth Fluoridation, Spectrophotometric Analysis, Tooth Imaging.


Integrated Carbon Dioxide Monitoring, Alarm, and Data Logging System for Closed Vehicle Environments

Charumati Seetharaman

Sishu Griha Senior School, 3, HAL 3rd Stage, New Tippasandra, Bengaluru, Karnataka 560075, India; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 64-69
Download Article: https://doi.org/10.36838/v7i12.64

KEYWORDS: Embedded Systems, Sensors, Indoor Air Quality, Carbon Dioxide, Automobiles.


The Impact of Synthetic Music Visualization on the Music Perception of Deaf and Hard of Hearing (DHH) Teenagers

Grace Xinya Ma

Chinese International School, 1 Hau Yuen Path, Braemar Hill, Hong Kong SAR, China; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 70-78
Download Article: https://doi.org/10.36838/v7i12.70

KEYWORDS: Biomedical Engineering, Neuroscience; Neurodevelopmental, Deaf and Hard of Hearing Teenagers, Human/Machine Interface, Music Visualization.


Machine Learning Predictions of Excessive Drinking and Social Determinants of Health Markers in Carolinas

Alex Haopeng Liu1, Anthony Haitao Zou2

1. Cary Academy, 1500 N Harrison Ave, Cary, NC 27513, USA
2. River Bluff High School, 320 Corley Mill Road, Lexington, SC, 29072, USA; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 79-86
Download Article: https://doi.org/10.36838/v7i12.79

KEYWORDS: Behavioral and Social Sciences, County-Level Prediction, Excessive Drinking, Sociology and Social Psychology.


Investigating the Role of the Gut-Brain Axis in Parkinson's Disease: from Dysbiosis to the Vagus Nerve

Roselyn Bi

River Hill High School, 12102 Clarksville Pike, Clarksville, Maryland, 21029, USA; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 87-94
Download Article: https://doi.org/10.36838/v7i12.87

KEYWORDS: Biomedical and Health Sciences, Pathophysiology, Parkinson’s Disease, Gut-brain Axis, α-Synuclein Toxic Spread.


What Drives Health Disparities in Triple Negative Breast Cancer? An Ancestry Stratified Transcriptomic Profiling

Salma Fareed

Hathaway Brown School, 19600 N Park Blvd, Shaker Heights, OH 44122, [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 95-101
Download Article: https://doi.org/10.36838/v7i12.95

KEYWORDS: Computational Biology and Bioinformatics, Computational Epidemiology, Triple Negative Breast Cancer (TNBC), Ancestry, Health Disparities.


Mechanisms of Parkinson's Disease Pathology and Treatment

Alessandro Lanza

Westminster School, 17A Dean’s Yard, London, SW1P 3PB, UK; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 102-113
Download Article: https://doi.org/10.36838/v7i12.102

KEYWORDS: Biomedical and Health Sciences, Pathophysiology, Parkinson’s Disease, Neuroscience, Genetics.


Gesture Recognition for ADHD Diagnosis Using a Fidget Ball and Convolutional Neural Networks

Drishti Sethia1, Amanda Lai2, Jacqueline Wu3

1. Mission San Jose High School 41717 Palm Ave. Fremont, CA, [email protected]
2. Milpitas High School, 1285 Escuela Pkwy, Milpitas, CA 95035, USA
3. Taipei European School, Swire European Secondary Campus, 31 JianYe Road, ShiLin District, Taipei 11193, Taiwan
IJHSR 2025 Vol. 7 Issue 12 p. 114-120
Download Article: https://doi.org/10.36838/v7i12.114

KEYWORDS: Robots and Intelligent Machines, Machine Learning, Gesture Recognition, Fidgeting.


Examining Structural Shifts in China's Fitness Industry: The Decline of Traditional Gyms and the Rise of Digital Fitness

Yuanxi Lu

Raffles Institution, 1 Raffles Institution Ln, Singapore, Singapore, 575954, Singapore; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 121-131
Download Article: https://doi.org/10.36838/v7i12.121

KEYWORDS: Behavioral and Social Sciences, Other (Microeconomics and Behavioral Economics), Fitness Industry, Digital Fitness, Healthy China 2030.


The HER2 Story: From Gene to Protein to the First Precision Medicine-Based Treatment for HER2-Positive Cancer

Aryan U. Shah

Hopkinton High School, 90 Hayden Rowe Street, Hopkinton, MA 01748, USA; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 132-140
Download Article: https://doi.org/10.36838/v7i12.132

KEYWORDS: Cellular and Molecular Biology, Genetics, Bioinformatics, HER2/ERBB2, HER2-positive Cancers.


Could 3D-Printed Plastic Replace Traditional Aerospace Materials When Producing Rockets and Satellites?

Lok Teng Cheung

Queen Ethelburga’s Collegiate, Car Park F, Thorpe Underwood, Estate, York, Yorkshire, YO26 9SS, UK; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 141-153
Download Article: https://doi.org/10.36838/v7i12.141

KEYWORDS: Aerospace and Aeronautical Engineering, Condensed Matter and Materials Mechanics, 3D Printing, Plastic, in-space Manufacturing.


An Overview of the Challenger STS-51L Accident and Its Implications on American Space Exploration

Bowen Wu

Beijing No.101 High School, Yiheyuan Road No.11, Haidian District, Beijing, 100084, China; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 154-158
Download Article: https://doi.org/10.36838/v7i12.154

KEYWORDS: Aerospace and Aeronautical Engineering, Space Shuttle, Challenger STS-51L Accident.


Evaluation of Harmful Substances in Menstrual Products: A Review

Michelle Chimdy Onyebuchi

Dawson College, 3040 Sherbrooke St W, Montreal, Quebec H3Z 1A4, Canada; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 159-167
Download Article: https://doi.org/10.36838/v7i12.159

KEYWORDS: Women’s Health, Environmental Exposures, Feminine Hygiene Products, Menstrual Products, Heavy Metals, Volatile Organic Compounds, Dioxins.


Improving Solar Panel Efficiency with Thermoelectric Generator (TEG) Powered Fan Cooling

William Y. Song, Jerry Chang

Oak Park High School, 899 Kanan Road, Oak Park, CA, 91377, USA; [email protected]
IJHSR 2025 Vol. 7 Issue 12 p. 168-172
Download Article: https://doi.org/10.36838/v7i12.168

KEYWORDS: Energy: Physical, Solar, Solar Panel Efficiency, Active Cooling, Thermoelectric Generator.